Student Poster Abstracts: Development of a Time Resolved FRET High-Throughput Assay to Identify Inhibitors of the RGS4/Gαo Interaction

Dr. Wensel received his Ph.D. in chemistry from the University of California, Davis. He then moved on to Stanford University as a post-doctoral fellow where he studied with Lubert Stryer. Currently, Dr. Wensel is professor of biochemistry & molecular biology at the Baylor College of Medicine, where his research focuses on signal transduction of G-protein coupled receptors in the retina and brain. Recent work in his laboratory has yielded considerable insight into the role that Regulator of G-Protein Signaling (RGS) proteins play in visual signal transduction. Using a vast array of techniques including X-ray crystallography, membrane biochemistry, and whole animal genetic manipulation, he aims to characterize the molecular mechanisms that are crucial for the proper regulation of GPCR signaling in the central nervous system.